The FINGER trial is the first randomized controlled trial showing that it is possible to prevent cognitive decline using a multi-domain lifestyle intervention among older at-risk individuals. The results highlighted the value of addressing multiple dementia risk factors as a strategy to protect brain health, and promote overall health and functioning.

The FINGER model is now being replicated in the United States, Europe, Singapore, and Australia – including populations from a variety of geographical and cultural backgrounds. This worldwide effort, collectively referred to as WW-FINGERS, supports a collaborative network of trials and experienced investigators to facilitate harmonization of research methods, and sharing of experiences and data for maximum global scientific impact.